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口腔恶性黑色素瘤——病例报告及文献综述

Malignant melanoma of the oral cavity--case reports and review of literature.

作者信息

Sivakumar G, Sivapathasundharam B, Karthiga Kannan S

机构信息

Department of Oral and Maxillo Facial Pathology, Meenakshi Ammal Dental College and Hospital, Maduravoyal, Chennai 600 095.

出版信息

Indian J Dent Res. 2004 Apr-Jun;15(2):70-3.

Abstract

Melanoma is a malignant tumor of melanocytes or their precursor cells. It is the third most common skin cancer and is one of the most biologically unpredictable neoplasms. Sunlight is an important etiological factor in cutaneous melanoma. Oral melanoma is relatively uncommon, exhibiting a definite predilection for palate and maxillary gingiva, and is twice as common in males as in females. We herewith report three cases of oral melanoma out of which two occurred on the palate and one in the maxillary gingiva. Their clinical presentations, histopathology and management are discussed.

摘要

黑色素瘤是黑素细胞或其前体细胞的恶性肿瘤。它是第三常见的皮肤癌,也是生物学上最不可预测的肿瘤之一。阳光是皮肤黑色素瘤的一个重要病因。口腔黑色素瘤相对少见,明显好发于腭部和上颌牙龈,男性发病率是女性的两倍。我们在此报告三例口腔黑色素瘤,其中两例发生在腭部,一例发生在上颌牙龈。对其临床表现、组织病理学及治疗进行了讨论。

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