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乙型和丙型肝炎患者肝移植的最新进展。

An update in liver transplantation in patients with hepatitis B and hepatitis C.

作者信息

Montalbano M, Neff G W

机构信息

ISMETT, University of Pittsburgh, USA.

出版信息

Minerva Gastroenterol Dietol. 2005 Mar;51(1):109-26.

Abstract

Chronic hepatitis C virus (HCV) infection is an epidemic that currently represents the number one indication for liver transplantation (LTx). Hepatitis B virus (HBV) infection is associated with better outcomes following LTx since the advent of hepatitis B immune globulin and lamivudine. The impact of HCV and HBV in LTx is well known. Therapeutic interventions, however, are less standardized and often depend upon institutional protocol. This review article will provide a comprehensive review of the literature and address many issues and complications with transplantation in patients suffering from chronic liver disease as a result of HCV or HBV.

摘要

慢性丙型肝炎病毒(HCV)感染是一种流行病,目前是肝移植(LTx)的首要指征。自乙肝免疫球蛋白和拉米夫定问世以来,乙肝病毒(HBV)感染与肝移植后较好的预后相关。HCV和HBV对肝移植的影响已为人熟知。然而,治疗干预措施的标准化程度较低,且往往取决于机构方案。这篇综述文章将对文献进行全面综述,并探讨因HCV或HBV导致慢性肝病患者移植中的诸多问题和并发症。

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