腐胺掺入量与转铁蛋白摄取量在大鼠网织红细胞中同时增加。

Concomitant increase in putrescine incorporation with transferrin uptake into rat reticulocytes.

作者信息

Katoh S, Ishii Y, Ohba Y, Kohno H, Ohkubo Y

机构信息

Department of Radiopharmacy, Tohoku College of Pharmacy, Sendai, Japan.

出版信息

Chem Pharm Bull (Tokyo). 1992 Jan;40(1):258-60. doi: 10.1248/cpb.40.258.

DOI:10.1248/cpb.40.258

PMID:1576682

Abstract

Concomitant increase in putrescine incorporation with transferrin uptake into rat reticulocytes was found. [14C]Putrescine incorporation occurred in the presence of transferrin at 37 degrees C. The subcellular distribution of incorporated [14C]putrescine showed that the incorporation in the plasma membrane time dependently increased. Both 125I-labeled transferrin uptake and [14C]putrescine incorporation decreased when ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid was added, while it increased with the addition of A23187.

摘要

发现腐胺掺入与转铁蛋白摄取进入大鼠网织红细胞的过程同时增加。在转铁蛋白存在的情况下，于37℃发生了[14C]腐胺的掺入。掺入的[14C]腐胺的亚细胞分布表明，质膜中的掺入随时间依赖性增加。当加入乙二醇双(2-氨基乙醚)-N,N,N',N'-四乙酸时，125I标记的转铁蛋白摄取和[14C]腐胺掺入均减少，而加入A23187时则增加。