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[江西省靖安县宫颈癌队列研究]

[A cohort study on cancer of uterine cervix in Jingan county, Jiangxi province].

作者信息

Yang X Z

机构信息

Jiangxi Provincial Gyn. & Obs. Hospital, Nanchang.

出版信息

Zhonghua Zhong Liu Za Zhi. 1992 Nov;13(6):409-12.

PMID:1576904
Abstract

A cohort study on 24,628 married women beyond 30 years of age in Jingan county, Jiangxi province was carried out from 1974 to 1985. It was equivalent to 207,490 person-year. The results showed that the earlier the first sexual intercourse the higher the risk of cervical cancer. There was a significant linear trend. The relative risk (RR) of cervical cancer in women increased from 1.63 to 6.85 with increase in the number of sex partners from one to two or more. The risk also increased from 1.44 to 5.38 and 2.69 as their husband had one, two or three and more extramarital sex partners. Irregular menstruation and insanitary mentrual pads were also risk factors. Risk factors of menarche age, age of first delivery, number of children, smoking and drinking were balanced in the present analysis by the logistic regression model.

摘要

1974年至1985年,对江西省靖安县24628名30岁以上已婚女性进行了一项队列研究。该研究相当于207490人年。结果显示,首次性行为越早,患宫颈癌的风险越高。存在显著的线性趋势。随着性伴侣数量从1个增加到2个或更多,女性患宫颈癌的相对风险(RR)从1.63增加到6.85。当她们的丈夫有1个、2个、3个或更多婚外性伴侣时,风险也分别从1.44增加到5.38和2.69。月经不调和不卫生的卫生巾也是危险因素。在本分析中,通过逻辑回归模型对初潮年龄、首次分娩年龄、子女数量、吸烟和饮酒等危险因素进行了平衡。

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