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[饮食与前列腺癌:从预防到治疗]

[Diet and prostate cancer: from prevention to treatment].

作者信息

Amsellem-Ouazana Delphine, Conquy Sophie

机构信息

Service d'Urologie, Hôpital Cochin, Paris, France.

出版信息

Prog Urol. 2004 Sep;14(4):573-6.

Abstract

Prostate cancer, the most frequent cancer in men over the age of 50, appears to be associated with certain nutritional risk factors. The role of these factors is revealed by epidemiological data (variation of prostate cancer incidence according to various regions of the world, modification of these incidences in relation to migratory flows of certain populations) and eating habit studies. These findings are the basis for a number of studies designed to determine the ideal diet to prevent and, if possible, contribute to the treatment of prostate cancer. The fat intake, the type of fat, the absorption of vitamins, trace elements, antioxidants (beta-carotene, lycopene), phyto-oestrogens, including soybean or plant mixtures such as PC-SPES, may all constitute nutritional factors involved in prostatic carcinogenesis. However, although a review of the literature shows that some populations appear to be more effectively protected than others by their cultural consumption of particular substances, the link with efficacy, in terms of prevention, of a diet based on this substance administered to another population has yet to be demonstrated. Although the ideal diet is unknown at the present time, some of these ingredients appear to be good candidates, such as unsaturated fats, soybean proteins, carotenoids, lycopene and vitamin E.

摘要

前列腺癌是50岁以上男性中最常见的癌症,似乎与某些营养风险因素有关。这些因素的作用通过流行病学数据(前列腺癌发病率随世界不同地区的变化、某些人群迁移流动导致的发病率变化)和饮食习惯研究得以揭示。这些发现是许多旨在确定预防前列腺癌以及在可能情况下辅助治疗前列腺癌的理想饮食的研究的基础。脂肪摄入量、脂肪类型、维生素、微量元素、抗氧化剂(β-胡萝卜素、番茄红素)、植物雌激素(包括大豆或植物混合物如PC-SPES)的摄入,都可能构成参与前列腺癌发生的营养因素。然而,尽管文献综述表明,一些人群因其对特定物质的文化消费似乎比其他人群得到了更有效的保护,但基于这种物质的饮食对另一人群预防效果的关联尚未得到证实。尽管目前尚不清楚理想的饮食是什么,但其中一些成分似乎是不错的选择,如不饱和脂肪、大豆蛋白、类胡萝卜素、番茄红素和维生素E。

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