Yang Kai-Shiang, Chen Yeong-Fong, Lin Ken-Kuo, Hsiao Ching-Hsi
Department of Ophthalmology, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.
Cornea. 2005 Apr;24(3):344-6. doi: 10.1097/01.ico.0000139635.95777.51.
We present a case of Mycobacterium keratitis after laser in situ keratomileusis (LASIK).
A retrospective case report.
A 40-year-old woman developed Mycobacterium chelonae keratitis in the right eye 2 weeks after bilateral LASIK. The diagnosis was made by acid-fast staining of corneal scrapings on admission and confirmed by culture results 2 weeks later. Intensive treatment with topical amikacin (25 mg/mL) and ciprofloxacin and partial excision of the flap led to resolution of the infection after 2 months of therapy. In addition, topical methylprednisolone (1 mg/mL) was necessary to control inflammation and pain. No recurrence was found during the 1-year follow-up period. The final uncorrected and corrected visual acuity in the right eye was 20/25 and 20/20, respectively.
Mycobacterium keratitis is a potentially vision-threatening complication after LASIK. Early recognition of the organisms and aggressive treatment if infection develops may improve the outcome. When surgery is indicated, partial flap amputation, which may help to resolve the infection and preserve better vision, may be considered.
我们报告一例准分子原位角膜磨镶术(LASIK)后发生的分枝杆菌性角膜炎病例。
一项回顾性病例报告。
一名40岁女性在双眼LASIK术后2周右眼发生龟分枝杆菌角膜炎。入院时通过角膜刮片抗酸染色做出诊断,并在2周后通过培养结果得以证实。局部使用阿米卡星(25mg/mL)和环丙沙星强化治疗以及部分角膜瓣切除术后,经过2个月的治疗感染得到控制。此外,需要局部使用甲基泼尼松龙(1mg/mL)来控制炎症和疼痛。在1年的随访期内未发现复发。右眼最终的未矫正视力和矫正视力分别为20/25和20/20。
分枝杆菌性角膜炎是LASIK术后一种潜在的视力威胁性并发症。早期识别病原体并在感染发生时积极治疗可能会改善预后。当需要进行手术时,可以考虑部分角膜瓣切除术,这可能有助于控制感染并保留更好的视力。