动眼神经植物动力学中广泛时间尺度的证据：对眼球运动控制模型的启示。
Evidence for wide range of time scales in oculomotor plant dynamics: implications for models of eye-movement control.
作者信息
Sklavos Sokratis, Porrill John, Kaneko Chris R S, Dean Paul
机构信息
Medical School, University of Patras, 26500 Patras, Greece.
出版信息
Vision Res. 2005 Jun;45(12):1525-42. doi: 10.1016/j.visres.2005.01.005.
Abstract
Oculomotor-plant dynamics are not well characterised, despite their importance for modelling eye-movement control. We analysed the time course of the globe's return after horizontal displacements in three rhesus monkeys lightly anaesthetised with ketamine. The eye-position traces were well fitted by a sum of four exponentials (time constants 0.012, 0.099, 0.46, 7.8 s). The two long time-constant terms accounted for 25% of plant compliance, and led to a model that accounted for hitherto unexplained features of ocular motoneuron firing such as (i) hysteresis, and (ii) the inability of a 2 time-constant model to fit data for both fast and slow eye-movements.
摘要
尽管动眼神经-眼球运动系统动力学对于眼球运动控制建模很重要，但其特征尚未得到充分描述。我们分析了三只用氯胺酮轻度麻醉的恒河猴在水平位移后眼球返回的时间进程。眼球位置轨迹可以很好地用四个指数函数之和来拟合（时间常数分别为0.012、0.099、0.46、7.8秒）。两个长时时间常数项占眼球运动系统顺应性的25%，并由此得到一个模型，该模型能够解释此前无法解释的眼运动神经元放电特征，如（i）滞后现象，以及（ii）双时间常数模型无法同时拟合快速和慢速眼球运动数据的问题。
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