Johnson S J, Sheffield E A, McNicol A M
Department of Cellular Pathology, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK.
J Clin Pathol. 2005 Apr;58(4):338-42. doi: 10.1136/jcp.2002.002550.
The pathological examination of parathyroid glands is an essential component of the evaluation of hyperparathyroidism. Traditionally, this has involved intraoperative frozen sections during bilateral surgical exploration of the neck, to confirm removal of parathyroid tissue. With recent developments in imaging, some diseased glands can be localised preoperatively, enabling removal by minimally invasive, targetted surgery, with or without additional non-histological intraoperative procedures to confirm the removal of all hyperfunctioning parathyroid tissue. This article reviews these developments and describes the ideal approach to reporting parathyroid specimens.
甲状旁腺的病理检查是评估甲状旁腺功能亢进的重要组成部分。传统上,这需要在颈部双侧手术探查期间进行术中冰冻切片,以确认甲状旁腺组织已被切除。随着影像学的最新发展,一些病变腺体可以在术前定位,从而能够通过微创靶向手术进行切除,无论是否需要额外的非组织学术中程序来确认所有功能亢进的甲状旁腺组织均已被切除。本文回顾了这些进展,并描述了报告甲状旁腺标本的理想方法。