Rosenthal D, Wellons E D, Lai K M, Bikk A
Department of Vascular Sugery, Atlanta Medical Center, Atlanta, GA, USA.
J Cardiovasc Surg (Torino). 2005 Apr;46(2):163-9.
Multiple-trauma patients often have injuries that prevent the use of anticoagulant or sequential compression device prophylaxis. Temporary inferior vena cava filters (IVCFs) offer protection against pulmonary embolism (PE) during the early, highest-risk perioperative and immediate injury period, while avoiding potential long-term sequelae of a permanent IVCF. The objective of this study was to evaluate the efficacy of prophylactic, temporary IVCF placement at the intensive care unit (ICU) bedside under real-time intravascular ultrasound (IVUS) guidance in multiple-trauma patients.
One hundred and three multiple-trauma patients between July 1, 2002, and July 1, 2004, under-went placement of Günther-Tulip (n=38), Recovery (n=30) or OptEase (n=35) retrievable IVCFs under real-time IVUS guidance. The mean+/-SD injury severity score of the patients was 27.7 (+/-2.2). All patients had abdominal X-rays to verify filter location. Before IVCF retrieval, all patients underwent femoral vein color-flow ultrasonography to rule out deep vein thrombosis (DVT) and pre and postprocedure vena-cavography for possible IVCF thrombus entrapment and postretrieval IVC injury.
Twenty-four patients died of their injuries; no deaths were related to IVCF placement. One PE occurred during follow-up after filter retrieval, and 2 insertion site femoral vein DVT occurred. As verified by abdominal X-rays, 97.1% (100/103) of IVCFs were placed without complications at the L2-3 level. Filter-related complications included 3 groin hematomas (2.9%) and 3 IVCFs misplaced in the right iliac vein early in our experience; these filters were uneventfully retrieved and replaced in the IVC within 24 h. Forty-four patients underwent uneventful retrieval of IVCFs after DVT or PE anticoagulation prophylaxis was initiated. Thirty-five filters were not removed, including 32 because severity of injury prevented DVT or PE prophylaxis and 3 because of thrombus trapped with the filter.
Prophylactic, temporary IVCFs placed at the ICU bedside under IVUS guidance in multiple-trauma patients serves as an effective bridge to anticoagulation until venous thromboembolism prophylaxis can be initiated. Further investigation of this bedside technique and the role of temporary IVCFs in these patients is warranted.
多发伤患者常因受伤而无法使用抗凝剂或序贯加压装置进行预防。临时性下腔静脉滤器(IVCF)可在围手术期早期、风险最高的阶段以及损伤即刻为患者提供预防肺栓塞(PE)的保护,同时避免永久性IVCF可能带来的长期后遗症。本研究的目的是评估在实时血管内超声(IVUS)引导下于重症监护病房(ICU)床旁预防性置入临时性IVCF在多发伤患者中的疗效。
2002年7月1日至2004年7月1日期间,103例多发伤患者在实时IVUS引导下置入了Günther-Tulip(n = 38)、Recovery(n = 30)或OptEase(n = 35)可回收IVCF。患者的平均损伤严重程度评分为27.7(±2.2)。所有患者均进行腹部X线检查以确认滤器位置。在取出IVCF之前,所有患者均接受股静脉彩色血流超声检查以排除深静脉血栓形成(DVT),并在操作前后进行腔静脉造影以检查是否有IVCF血栓截留及取出后腔静脉损伤情况。
24例患者因伤死亡;无死亡与IVCF置入相关。滤器取出后的随访期间发生1例PE,2例出现置入部位股静脉DVT。经腹部X线检查证实,97.1%(100/103)的IVCF在L2 - 3水平置入且无并发症。与滤器相关的并发症包括3例腹股沟血肿(2.9%)以及在我们早期经验中有3例IVCF误置于右髂静脉;这些滤器均在24小时内顺利取出并重新置入下腔静脉。44例患者在开始进行DVT或PE抗凝预防后顺利取出IVCF。35个滤器未取出,其中32个是因为损伤严重程度妨碍了DVT或PE预防,3个是因为滤器截留血栓。
在多发伤患者中,于IVUS引导下在ICU床旁预防性置入临时性IVCF可作为抗凝治疗的有效桥梁,直至能够开始进行静脉血栓栓塞预防。有必要对这种床旁技术以及临时性IVCF在这些患者中的作用进行进一步研究。