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[Trisomy 18 (Edwards syndrome): two case reports].

作者信息

Morosini P, Verdura C, Paolillo F, Fornari M, Argentiero M L, Belloni C

机构信息

Divisione di Patologia Neonatale, Ospedale Maggiore di Lodi Mi, Italia.

出版信息

Pediatr Med Chir. 1992 Jan-Feb;14(1):75-7.

PMID:1579521
Abstract

Edwards (or trisomy 18) syndrome, with a frequency of about 1 over 8000 births, is commonly characterized by a very short survival; those rare cases reported with ages of 12 months or more, always were demonstrated to be chromosomic mosaicisms. Two affected children with completely different outcomes are here described; the first with a classic short-life evolution, in opposition to the second with long survival, the last a good example of all those various biological, psychological and social support interventions in these circumstances, very rare to match with, for this appears to be a trisomy 18 without mosaicism.

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