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远外侧小脑上幕下入路治疗脑干上部胶质瘤:小儿患者的临床经验

Far lateral supracerebellar infratentorial approach for the treatment of upper brainstem gliomas: clinical experience with pediatric patients.

作者信息

Vougioukas Vassilios I, Omran Heymut, Gläsker Sven, Van Velthoven Vera

机构信息

Department of Neurosurgery, Neurocenter, Albert-Ludwigs-University of Freiburg, Breisacherstrasse 64, 79106, Freiburg im Breisgau, Germany.

出版信息

Childs Nerv Syst. 2005 Dec;21(12):1037-41. doi: 10.1007/s00381-005-1140-6. Epub 2005 Mar 31.

Abstract

OBJECTIVE

Surgical exposure of intrinsic lesions located lateral to the brainstem still represents a challenging task. The aim of this study was to assess the feasibility of the extracerebral far lateral supracerebellar infratentorial (FLSI) approach for the treatment of gliomas located in the upper brainstem in the pediatric population.

METHODS AND RESULTS

Between 1992 and 2002, seven patients (mean age 8.7 years) with tumors of glial origin (WHO I-IV) located mainly in the pontomesencephalic region were operated with the FLSI approach in a sitting position. Satisfactory extent of resection without additional morbidity was achieved.

CONCLUSION

In a carefully selected pediatric patient population, the FLSI approach proved to be a feasible and effective surgical route for the treatment of upper brainstem gliomas.

摘要

目的

手术暴露位于脑干外侧的内在病变仍然是一项具有挑战性的任务。本研究的目的是评估脑外远外侧小脑上幕下(FLSI)入路治疗小儿人群中位于上脑干的胶质瘤的可行性。

方法与结果

1992年至2002年间,7例(平均年龄8.7岁)主要位于脑桥中脑区域的神经胶质源性肿瘤(世界卫生组织I-IV级)患者采用FLSI入路坐位手术。实现了满意的切除范围且无额外的并发症。

结论

在经过精心挑选的小儿患者群体中,FLSI入路被证明是治疗上脑干胶质瘤的一种可行且有效的手术途径。

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