Cashman J R, Maltby D A, Nishioka R S, Bern H A, Gee S J, Hammock B D
Department of Pharmaceutical Chemistry, University of California, San Francisco 94143.
Chem Res Toxicol. 1992 Jan-Feb;5(1):100-5. doi: 10.1021/tx00025a017.
In 1987, striped bass (Morone saxatilis) that were nearly dead (moribund) were captured by hand net, and apparently healthy striped bass were caught by hook and line from adjacent waters in the Sacramento-San Joaquin Delta or, alternatively, caught by hook and line from the Pacific Ocean. The livers of these three groups of striped bass were examined for chemical contamination by gas chromatography, by gas chromatography-mass spectrometry, and by immunoassay. Moribund striped bass livers were greatly contaminated by chemicals compared to healthy fish caught in the Delta and the Pacific Ocean. The types of contaminant encountered suggested that industrial, agricultural, and urban pollutants were present in the livers of moribund fish. Although the variability in the amount of hepatic contaminants observed among the groups of fish does not provide direct proof of causation, the large amount of pollutants suggests that chemical contamination (possibly acting as multiple stressors) contributes to the hepatotoxic condition of the moribund striped bass and may lead to an explanation of the die-off in the Sacramento-San Joaquin Delta region.
1987年,用手网捕获了几近死亡(濒死)的条纹鲈(Morone saxatilis),并通过钩钓从萨克拉门托-圣华金河三角洲的相邻水域捕获了看似健康的条纹鲈,或者从太平洋用钩钓捕获。通过气相色谱法、气相色谱-质谱法和免疫分析法对这三组条纹鲈的肝脏进行化学污染物检测。与在三角洲和太平洋捕获的健康鱼类相比,濒死条纹鲈的肝脏受到了严重的化学污染。所遇到的污染物类型表明,濒死鱼类的肝脏中存在工业、农业和城市污染物。尽管在不同组鱼类中观察到的肝脏污染物含量差异并不能直接证明因果关系,但大量污染物表明化学污染(可能作为多种应激源)导致了濒死条纹鲈的肝毒性状况,并可能为萨克拉门托-圣华金河三角洲地区的鱼类死亡提供一种解释。