朗格汉斯细胞组织细胞增多症：一例无骨骼受累的临床病例。
Langerhans-cell histiocytosis: a clinical case without bone involvement.
作者信息
Manfredi M, Corradi D, Vescovi P
机构信息
Department of Otorhino-Laryngology and Ophthalmology, Dental and Maxillo-Facial Sciences, Dentistry and Oral Medicine Section, University of Parma, Parma, Italy.
出版信息
J Periodontol. 2005 Jan;76(1):143-7. doi: 10.1902/jop.2005.76.1.143.
BACKGROUND
Langerhans-cell histiocytosis (LCH) is a group of rare disorders histologically characterized by the proliferation of Langerhans cells. Multiple organs and systems may be involved by the disease. Typically, there is bone involvement and, less frequently, lesions may be found in the lungs, liver, lymph nodes, skin, and mucosae. Oral soft tissue lesions without bone involvement are rare.
METHODS
We report a case of a 23-year-old man with LCH detected by oral soft tissue, cutaneous, and lung lesions.
RESULTS
Due to the oral lesion diagnosis, important procedures were performed, which determined the staging of the disease.
CONCLUSION
Gingival lesions could be one of the first manifestations of LCH. The periodontist should recognize and detect this important pathology with oral involvement.
背景
朗格汉斯细胞组织细胞增多症（LCH）是一组罕见疾病，组织学上以朗格汉斯细胞增殖为特征。该疾病可累及多个器官和系统。通常会出现骨骼受累，较少见的是肺部、肝脏、淋巴结、皮肤和黏膜出现病变。无骨骼受累的口腔软组织病变较为罕见。
方法
我们报告一例23岁男性患者，通过口腔软组织、皮肤和肺部病变确诊为LCH。
结果
由于口腔病变的诊断，进行了重要的检查程序，从而确定了疾病分期。
结论
牙龈病变可能是LCH的首发表现之一。牙周病医生应认识并检测出这种伴有口腔受累的重要病理情况。
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