肱骨尤因肉瘤在影像学和生物学行为上酷似骨纤维发育不良。

Ewing's sarcoma of the humerus mimicking fibrous dysplasia on imaging and biological behavior.

作者信息

Sundaram Murali, Inwards Carrie Y, Shives Thomas E, Anderson Peter M

机构信息

Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.

出版信息

Skeletal Radiol. 2005 May;34(5):285-9. doi: 10.1007/s00256-004-0847-x. Epub 2004 Nov 11.

DOI:10.1007/s00256-004-0847-x

PMID:15838704

Abstract

We present the case of a 12-year-old girl who presented with a pathological fracture through a benign-appearing osteolytic lesion that was presumed to represent fibrous dysplasia. The fracture healed, and over the next 2.5 years there was further refracturing and healing with progressive osteolysis. A biopsy was performed and revealed Ewing's sarcoma. The disease was locally controlled by neoadjuvant chemotherapy and radiation therapy. The patient is disease free with excellent function 6 years following the discovery of the lesion. We illustrate and discuss the sequence of events.

摘要

我们报告了一名12岁女孩的病例，她因一处看似良性的溶骨性病变出现病理性骨折，该病变被推测为纤维发育不良。骨折愈合，在接下来的2.5年里，随着骨质溶解的进展，又出现了进一步的骨折和愈合。进行了活检，结果显示为尤因肉瘤。通过新辅助化疗和放射治疗对该疾病进行了局部控制。在发现病变6年后，患者无疾病且功能良好。我们展示并讨论了一系列事件。