64层螺旋CT冠状动脉造影的准确性：初步经验

Accuracy of MSCT coronary angiography with 64-slice technology: first experience.

作者信息

Leschka Sebastian, Alkadhi Hatem, Plass André, Desbiolles Lotus, Grünenfelder Jürg, Marincek Borut, Wildermuth Simon

机构信息

Department of Medical Radiology, Institute of Diagnostic Radiology, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.

出版信息

Eur Heart J. 2005 Aug;26(15):1482-7. doi: 10.1093/eurheartj/ehi261. Epub 2005 Apr 19.

DOI:10.1093/eurheartj/ehi261

PMID:15840624

Abstract

AIMS

The aim of our study was to investigate the accuracy of 64-slice computed tomography (CT) for assessing haemodynamically significant stenoses of coronary arteries.

METHODS AND RESULTS

CT angiography was performed in 67 patients (50 male, 17 female; mean age 60.1+/-10.5 years) with suspected coronary artery disease and compared with invasive coronary angiography. All vessels > or =1.5 mm were considered for the assessment of significant coronary artery stenosis (diameter reduction >50%). Forty-seven patients were identified as having significant coronary stenoses on invasive angiography with 18% (176/1005) affected segments. None of the coronary segments needed to be excluded from analysis. CT correctly identified all 20 patients having no significant stenosis on invasive angiography. Overall sensitivity for classifying stenoses was 94%, specificity was 97%, positive predictive value was 87%, and negative predictive value was 99%.

CONCLUSION

Sixty-four-slice CT provides a high diagnostic accuracy in assessing coronary artery stenoses.

摘要

目的

本研究旨在探讨64层计算机断层扫描（CT）评估冠状动脉血流动力学显著狭窄的准确性。

方法与结果

对67例疑似冠心病患者（50例男性，17例女性；平均年龄60.1±10.5岁）进行CT血管造影，并与有创冠状动脉造影进行比较。所有直径≥1.5 mm的血管均纳入显著冠状动脉狭窄（直径减少>50%）的评估。47例患者在有创血管造影中被确定为有显著冠状动脉狭窄，累及节段占18%（176/1005）。所有冠状动脉节段均无需排除在分析之外。CT正确识别出所有20例在有创血管造影中无显著狭窄的患者。总体而言，狭窄分类的敏感性为94%，特异性为97%，阳性预测值为87%，阴性预测值为99%。