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[1例活动性溃疡性结肠炎合并肺血栓栓塞症]

[A case of pulmonary thromboembolism in active ulcerative colitis].

作者信息

Park Jae Han, Choi Gueng Sung, Kim Myoung Seok, Kim Hyung Keun, Cho Young Seok, Son Seong Hyun, Kim Chang Wook, Chae Hiun Suk, Lee Chang Don, Choi Kyu Young, Chung In Sik

机构信息

Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.

出版信息

Korean J Gastroenterol. 2005 Apr;45(4):301-5.

Abstract

Thromboembolic disease is a significant cause of morbidity and mortality in patients with inflammatory bowel disease. The reported incidence is 1-6%. The most common thromboembolic complications are deep venous thrombosis of legs and pulmonary thromboembolism. Cerebral thrombosis, portal vein thrombosis, retinal venous thrombosis and arterial thrombosis were also reported. We experienced a case of ulcerative colitis complicated with pulmonary thromboembolism. The patient was a 70-year-old woman who was diagnosed as ulcerative colitis on colonoscopy. We used prednisolone and sulfasalazine for the treatment of ulcerative colitis. Twenty five days later, she complained of abrupt dyspnea and chest pain. Chest CT and ventilation-perfusion scan revealed a thromboembolism in both lung. After the treatment of heparin & warfarin therapy, follow-up chest CT showed much regressed pulmonary thromboembolism. We report a 70-year-old woman with ulcerative colitis complicated with pulmonary thromboembolism and treated with heparin & warfarin therapy successfully.

摘要

血栓栓塞性疾病是炎症性肠病患者发病和死亡的重要原因。报告的发病率为1%-6%。最常见的血栓栓塞并发症是下肢深静脉血栓形成和肺血栓栓塞。也有关于脑血栓形成、门静脉血栓形成、视网膜静脉血栓形成和动脉血栓形成的报道。我们遇到了一例溃疡性结肠炎并发肺血栓栓塞的病例。该患者是一名70岁女性,经结肠镜检查诊断为溃疡性结肠炎。我们使用泼尼松龙和柳氮磺胺吡啶治疗溃疡性结肠炎。25天后,她突然出现呼吸困难和胸痛。胸部CT和通气-灌注扫描显示双肺血栓栓塞。经过肝素和华法林治疗后,随访胸部CT显示肺血栓栓塞明显消退。我们报告了一名70岁患有溃疡性结肠炎并发肺血栓栓塞并成功接受肝素和华法林治疗的女性。

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