Scherberger Hansjörg, Jarvis Murray R, Andersen Richard A
Division of Biology, California Institute of Technology, Pasadena, California 91125, USA.
Neuron. 2005 Apr 21;46(2):347-54. doi: 10.1016/j.neuron.2005.03.004.
The cortical local field potential (LFP) is a summation signal of excitatory and inhibitory dendritic potentials that has recently become of increasing interest. We report that LFP signals in the parietal reach region (PRR) of the posterior parietal cortex of macaque monkeys have temporal structure that varies with the type of planned or executed motor behavior. LFP signals from PRR provide better decode performance for reaches compared to saccades and have stronger coherency with simultaneously recorded spiking activity during the planning of reach movements than during saccade planning. LFP signals predict the animal's behavioral state (e.g., planning a reach or saccade) and the direction of the currently planned movement from single-trial information. This new evidence provides further support for a role of the parietal cortex in movement planning and the potential application of LFP signals for a brain-machine interface.
皮层局部场电位（LFP）是兴奋性和抑制性树突电位的总和信号，最近越来越受到关注。我们报告称，猕猴后顶叶皮层顶叶够物区域（PRR）中的LFP信号具有随计划或执行的运动行为类型而变化的时间结构。与扫视相比，来自PRR的LFP信号在够物解码方面表现更好，并且在够物运动计划期间与同时记录的尖峰活动的相干性比扫视计划期间更强。LFP信号可根据单次试验信息预测动物的行为状态（例如，计划够物或扫视）以及当前计划运动的方向。这一新证据为顶叶皮层在运动计划中的作用以及LFP信号在脑机接口中的潜在应用提供了进一步支持。
