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[Evaluation of the activity of polymorphonuclear neutrophils against Entamoeba histolytica antigens].

作者信息

Manrique Osbert Rosales, Romero Haideé Urdaneta, Barrios Manuel Hernández, Muñoz José Francisco

机构信息

Instituto de Inmunología Clínica, Ula. Mérida-Venezuela.

出版信息

Rev Cubana Med Trop. 2002 May-Aug;54(2):96-100.

Abstract

This paper evaluates the production of superoxide as an indicator of the activity of neutrophils from healthy individuals, stimulated with Entamoeaba histolytica membrane antigens, chemical stimulators and antigens from other parasites. The kinetic nitroblue tetrazolium reduction test was used. No significant differences were observed in the control group as to superoxide production by neutrophils primed with Entamoeba histolytica antigens or Cisticercus cellulosae, Toxoplasma gondii and Giardia lamblia antigens. These results allow us to conclude that Entamoeba histolytica membrane antigens do not induce superoxide production by neutrophils, which contradicts previous statements on suppresed activity of neutrophils after they get in contact with Entamoeaba histolytica antigens.

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