Harle Deacon E, Evans Bruce J W
The Neville Chappell Research Clinic, The Institute of Optometry, Newington Causeway, London.
Ophthalmic Physiol Opt. 2005 May;25(3):233-9. doi: 10.1111/j.1475-1313.2005.00285.x.
The literature suggests that visual field defects may be more common in people who experience migraine. The Humphrey frequency doubling (FDT) visual field instrument selectively examines the magnocellular visual pathway, but has not previously been used to investigate visual function in migraine. In a masked controlled study we compared Humphrey FDT and Humphrey Swedish Interactive Threshold Algorithm fields of 25 migraine sufferers with 25 age- and gender-matched controls. Although both mean deviation and pattern standard deviation were a little worse in the migraine group, these differences did not reach statistical significance. There were no inter-eye visual field differences in the migraine group compared with controls. Comparing the mean of all the contrast thresholds in each hemisphere, there were no more inter-hemifield visual field differences in the migraine group compared with controls. There was no significant difference between the migraine and control groups in intra-ocular pressures. The visual field parameters were not correlated with the interval since the last migraine headache, the severity of migraine headache, the duration of migraine headache or the number of migraine headaches per annum. In our data, there was no evidence of visual field deficits, a magnocellular deficit, or indications of glaucomatous pathology.
文献表明,视野缺损在偏头痛患者中可能更为常见。汉弗莱倍频视野仪(FDT)可选择性地检测大细胞视觉通路,但此前尚未用于研究偏头痛患者的视觉功能。在一项双盲对照研究中,我们比较了25名偏头痛患者与25名年龄和性别匹配的对照者的汉弗莱FDT视野和汉弗莱瑞典交互式阈值算法视野。尽管偏头痛组的平均偏差和模式标准差均稍差,但这些差异未达到统计学显著性。与对照组相比,偏头痛组两眼间的视野无差异。比较每个半球所有对比度阈值的平均值,与对照组相比,偏头痛组半球间视野也无更多差异。偏头痛组和对照组的眼压无显著差异。视野参数与上次偏头痛发作后的间隔时间、偏头痛的严重程度、偏头痛的持续时间或每年偏头痛发作的次数均无相关性。在我们的数据中,没有证据表明存在视野缺损、大细胞缺陷或青光眼病理迹象。