Caplan Rochelle, Siddarth Prabha, Gurbani Suresh, Hanson Rebecca, Sankar Ramen, Shields W Donald
Department of Psychiatry, University of California at Los Angeles, 90024, USA.
Epilepsia. 2005 May;46(5):720-30. doi: 10.1111/j.1528-1167.2005.43604.x.
This study examined affective disorders, anxiety disorders, and suicidality in children with epilepsy and their association with seizure-related, cognitive, linguistic, family history, social competence, and demographic variables.
A structured psychiatric interview, mood self-report scales, as well as cognitive and language testing were administered to 100 children with complex partial seizures (CPSs), 71 children with childhood absence epilepsy (CAE), and 93 normal children, aged 5 to 16 years. Parents provided behavioral information on each child through a structured psychiatric interview and behavior checklist.
Significantly more patients had affective and anxiety disorder diagnoses (33%) as well as suicidal ideation (20%) than did the normal group, but none had made a suicide attempt. Anxiety disorder was the most frequent diagnosis among the patients with a diagnosis of affective or anxiety disorders, and combined affective/anxiety and disruptive disorder diagnoses, in those with suicidal ideation. Only 33% received some form of mental health service. Age, verbal IQ, school problems, and seizure type were related to the presence of a diagnosis of affective or anxiety disorder, and duration of illness, to suicidal ideation.
These findings together with the high rate of unmet mental health underscore the importance of early detection and treatment of anxiety disorders and suicidal ideation children with CPSs and CAE.
本研究调查了癫痫患儿的情感障碍、焦虑障碍和自杀倾向,以及它们与癫痫相关、认知、语言、家族史、社会能力和人口统计学变量之间的关联。
对100名患有复杂部分性发作(CPS)的儿童、71名患有儿童失神癫痫(CAE)的儿童和93名年龄在5至16岁的正常儿童进行了结构化精神科访谈、情绪自评量表以及认知和语言测试。父母通过结构化精神科访谈和行为清单提供每个孩子的行为信息。
与正常组相比,患有情感和焦虑障碍诊断(33%)以及自杀意念(20%)的患者明显更多,但无人曾尝试自杀。焦虑障碍是患有情感或焦虑障碍诊断的患者中最常见的诊断,在有自杀意念的患者中,情感/焦虑合并破坏性行为障碍诊断也较为常见。只有33%的患者接受了某种形式的心理健康服务。年龄、言语智商、学校问题和癫痫发作类型与情感或焦虑障碍诊断的存在有关,而疾病持续时间与自杀意念有关。
这些发现以及未得到满足的心理健康的高发生率凸显了早期发现和治疗患有CPS和CAE的儿童的焦虑障碍和自杀意念的重要性。