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声门下气管狭窄作为喉边缘区B细胞淋巴瘤的主要表现。

Subglottic tracheal stenosis as primary manifestation of a marginal zone B-cell lymphoma of the larynx.

作者信息

Andratschke Michaela, Stelter Klaus, Ihrler Stephan, Hagedorn Hjalmar

机构信息

Department of Otorhinolaryngology, Ludwig-Maximilians-University of Munich, Germany.

出版信息

In Vivo. 2005 May-Jun;19(3):547-50.

Abstract

BACKGROUND

More than 90% of laryngeal tumors are squamous cell carcinomas. Primary hematopoetic neoplasms of the larynx are rare, being mainly extramedullary plasmocytoma and non-Hodgkin's lymphoma (NHL). These are mainly located in the supraglottic and glottic area, with only a few reported in the subglottic region.

CASE REPORT

We report on a 58-year-old man, who presented at our clinic with severe dyspnea. On microlaryngoscopy, a subglottic stenosis at the level of the cricoid cartilage was found. The biopsy revealed the diagnosis of a MALT-type lymphoma (marginal zone B-cell lymphoma). The tracheostomy was followed by locoregional radiotherapy.

CONCLUSION

This is the first report of a subglottic MALT-type lymphoma causing a tracheal stenosis. The preferred treatment is locoregional radiotherapy including the draining lymph nodes.

摘要

背景

超过90%的喉肿瘤为鳞状细胞癌。喉原发性造血系统肿瘤较为罕见,主要为髓外浆细胞瘤和非霍奇金淋巴瘤(NHL)。这些肿瘤主要位于声门上区和声门区,仅有少数报道位于声门下区。

病例报告

我们报告一名58岁男性,因严重呼吸困难前来我院就诊。显微喉镜检查发现环状软骨水平有声门下狭窄。活检确诊为黏膜相关淋巴组织型淋巴瘤(边缘区B细胞淋巴瘤)。气管切开术后进行了局部区域放疗。

结论

这是首例关于声门下黏膜相关淋巴组织型淋巴瘤导致气管狭窄的报告。首选治疗方法是包括引流淋巴结在内的局部区域放疗。

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