脊柱结核的治疗：一项回顾性研究。
The treatment of spinal tuberculosis: a retrospective study.
作者信息
Ramachandran S, Clifton I J, Collyns T A, Watson J P, Pearson S B
机构信息
Department of Respiratory Medicine, Leeds General Infirmary, Leeds, United Kingdom.
出版信息
Int J Tuberc Lung Dis. 2005 May;9(5):541-4.
BACKGROUND
There are conflicting guidelines and variations in clinical practice in the management of bone tuberculosis (TB), including spinal TB. A case who received 6 months of treatment in line with current British Thoracic Society (BTS) guidelines, and subsequently relapsed, prompted a survey of treatment and outcomes of spinal and other bone TB.
METHODS
A retrospective study examining the clinical features, treatment duration and outcome of patients presenting with spinal and other bone TB to the Leeds Teaching Hospitals National Health Service Trust, between 1998 and 2002.
RESULTS
Forty-two patients were identified. Notes from 34 patients with spinal TB and four patients with TB of other bones were reviewed. Of eight patients who received 6 months of therapy, five relapsed. Of 30 patients who received treatment for 9 months or longer, none relapsed (P < 0.05).
CONCLUSION
Six months of treatment, as currently recommended by the BTS, may be inadequate for bone TB, including spinal TB.
背景
在骨结核（包括脊柱结核）的管理方面，临床实践中存在相互冲突的指南和差异。有一例患者按照英国胸科学会（BTS）当前指南接受了6个月的治疗，但随后复发，这促使对脊柱结核和其他骨结核的治疗及结果进行了一项调查。
方法
一项回顾性研究，调查了1998年至2002年间在利兹教学医院国民保健服务信托基金就诊的脊柱结核和其他骨结核患者的临床特征、治疗时长和结果。
结果
共确定了42例患者。对34例脊柱结核患者和4例其他骨骼结核患者的病历进行了审查。在接受6个月治疗的8例患者中，5例复发。在接受9个月或更长时间治疗的30例患者中，无1例复发（P<0.05）。
结论
BTS目前推荐的6个月治疗时间对于包括脊柱结核在内的骨结核可能并不足够。
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