巴西大西洋热带森林植物的抗病毒评估
Antiviral evaluation of plants from Brazilian Atlantic Tropical Forest.
作者信息
Andrighetti-Fröhner C R, Sincero T C M, da Silva A C, Savi L A, Gaido C M, Bettega J M R, Mancini M, de Almeida M T R, Barbosa R A, Farias M R, Barardi C R M, Simões C M O
机构信息
Laboratório de Virologia Aplicada, Universidade Federal de Santa Catarina, Campus Universitário Trindade, Florianópolis, SC, Brazil.
出版信息
Fitoterapia. 2005 Jun;76(3-4):374-8. doi: 10.1016/j.fitote.2005.03.010.
The antiviral activity of six medicinal plants from Brazilian Atlantic Tropical Forest was investigated against two viruses: herpes simplex virus type 1 (HSV-1) and poliovirus type 2 (PV-2). Cuphea carthagenensis and Tillandsia usneoides extracts showed the best antiherpes activity. T. usneoides dichloromethane, ethyl acetate and n-butanol extracts, and Lippia alba n-butanol extract showed inhibition of HSV-1, strain 29R/acyclovir resistant. In addition, only L. alba ethyl acetate extract showed antipoliovirus activity. These results corroborate that medicinal plants can be a rich source of potential antiviral compounds.
对来自巴西大西洋热带森林的六种药用植物针对两种病毒
单纯疱疹病毒1型（HSV-1）和脊髓灰质炎病毒2型（PV-2）的抗病毒活性进行了研究。卡氏萼距花和松萝凤梨提取物表现出最佳的抗疱疹活性。松萝凤梨的二氯甲烷、乙酸乙酯和正丁醇提取物，以及白香蜂草的正丁醇提取物对HSV-1 29R/阿昔洛韦耐药株表现出抑制作用。此外，只有白香蜂草的乙酸乙酯提取物表现出抗脊髓灰质炎病毒活性。这些结果证实药用植物可能是潜在抗病毒化合物的丰富来源。
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