Albertario F, Ceriana P, Scelsi R, Geraci P, Azan G, Dionigi R V, Mapelli A
Servizio di Anestesia e Rianimazione 2. IRCCS Policlinico San Matteo, Pavia.
Minerva Anestesiol. 1992 Jan-Feb;58(1-2):19-25.
Disturbances of potassium homeostasis are frequently iatrogenic: some drugs, especially diuretics, are sometimes taken without proper electrolyte control and replacement; this can lead to more or less severe hypokalemic states. After some physiopathologic remarks, the Authors report their experience with four patients admitted for severe hypokalemia; the clinical picture was always quite typical: severe muscle weakness (even quadriparesis), cardiac rhythm abnormalities, metabolic alkalosis. A reliable diagnostic tool is muscle biopsy that shows aspects of vacuolar myopathy.