Harford Thomas C, Grant Bridget F, Yi Hsiao-Ye, Chen Chiung M
CSR, Incorporated, Arlington, Virginia 22201, USA.
Alcohol Clin Exp Res. 2005 May;29(5):810-28. doi: 10.1097/01.alc.0000164381.67723.76.
Studies of the prevalence of DSM-IV alcohol use disorders (AUDs) in general population samples of adolescents and adults are rare. Comparisons of the prevalence of alcohol abuse and dependence in adolescent surveys with the prevalence in adult general population surveys are confounded by differences in survey design and measurement, thereby reducing their validity. The purpose of the present study was to examine the effects of age, sex, race/ethnicity, and drinking status on the prevalence of DSM-IV alcohol abuse and dependence (including diagnostic orphans) and associated diagnostic criteria among adolescents and adults aged 12-65 years in a single representative sample of the US population.
This study was based on data from the 2001 National Household Survey on Drug Abuse public use file. Of the 55,561 subjects in the survey, 33,576 (60.5%) reported alcohol use in the past year and provided information on DSM-IV AUD criteria. DSM-IV AUD criteria were assessed by questions related to specific symptoms occurring during the past 12 months.
Overall, the most prevalent criteria of DSM-IV alcohol dependence were "tolerance" and "time spent obtaining alcohol, drinking, or getting over its effects." The most prevalent criterion of DSM-IV alcohol abuse was "hazardous use." The prevalence of alcohol abuse only and of dependence with and without abuse was highest among respondents aged 18-23 years, followed by respondents aged 12-17 years, and lowest among respondents aged 50 years and older. Among subgroups of current and heavier drinkers, differences between adolescents and young adults were less pronounced, especially among females. For each age group, the prevalence of alcohol abuse only was greater than the prevalence of dependence (with or without abuse). The abuse-to-dependence ratios also were generally consistent across age groups and slightly higher among males (2.1:1.0) than females (1.6:1.0).
The higher prevalence for some dependence criteria among adolescents and young adults as measured in the present study may blur the distinction between symptom reports associated with the normative development of drinking patterns and clinically relevant aspects of DSM-IV alcohol dependence.
针对青少年和成年人普通人群样本中《精神疾病诊断与统计手册》第四版(DSM-IV)酒精使用障碍(AUDs)患病率的研究较为罕见。青少年调查中酒精滥用和依赖的患病率与成年人普通人群调查中的患病率比较,因调查设计和测量方法的差异而受到混淆,从而降低了其效度。本研究的目的是在美国人群的单一代表性样本中,考察年龄、性别、种族/族裔和饮酒状况对12至65岁青少年和成年人中DSM-IV酒精滥用和依赖(包括诊断孤儿)患病率及相关诊断标准的影响。
本研究基于2001年全国药物滥用家庭调查公开使用文件中的数据。在调查的55561名受试者中,33576名(60.5%)报告在过去一年中饮酒,并提供了有关DSM-IV酒精使用障碍标准的信息。DSM-IV酒精使用障碍标准通过与过去12个月内出现的特定症状相关的问题进行评估。
总体而言,DSM-IV酒精依赖最常见的标准是“耐受性”和“花时间获取酒精、饮酒或消除其影响”。DSM-IV酒精滥用最常见的标准是“危险使用”。仅酒精滥用以及伴有或不伴有滥用的依赖的患病率在18至23岁的受访者中最高,其次是12至17岁的受访者,在50岁及以上的受访者中最低。在当前饮酒量较大的亚组中,青少年和年轻人之间的差异不太明显,尤其是在女性中。对于每个年龄组,仅酒精滥用的患病率高于依赖(伴有或不伴有滥用)的患病率。滥用与依赖的比例在各年龄组中总体也较为一致,男性(2.1:1.0)略高于女性(1.6:1.0)。
本研究中测量的青少年和年轻人中某些依赖标准的较高患病率可能会模糊与饮酒模式规范发展相关的症状报告与DSM-IV酒精依赖临床相关方面之间的区别。