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秋水仙碱单药治疗顽固性获得性大疱性表皮松解症(EBA)的缓解情况。

Remission of recalcitrant epidermolysis bullosa acquisita (EBA) with colchicine monotherapy.

作者信息

Arora Komal Pahuja, Sachdeva Bharti, Singh Navjeevan, Bhattacharya Sambit Nath

机构信息

Department of Dermatology & STD, UCMS & GTB Hospital, Dilshad Garden, Delhi-110095, India.

出版信息

J Dermatol. 2005 Feb;32(2):114-9. doi: 10.1111/j.1346-8138.2005.tb00727.x.

Abstract

A 42-year-old woman with widespread recalcitrant epidermolysis bullosa acquisita (EBA) responded well to colchicine monotherapy after attempts to control her disease with other modalities failed. These included dapsone, tetracycline, prednisolone, and combination of cyclophosphamide/azathioprine with dexamethasone 'pulse therapy'. The useful role of colchicine in controlling some difficult cases of EBA, a therapeutically problematic condition, is stressed.

摘要

一名42岁患有广泛难治性获得性大疱性表皮松解症(EBA)的女性,在尝试用其他方法控制病情失败后,秋水仙碱单一疗法对其疗效良好。这些方法包括氨苯砜、四环素、泼尼松龙,以及环磷酰胺/硫唑嘌呤与地塞米松“冲击疗法”的联合使用。强调了秋水仙碱在控制一些难治性EBA病例(一种治疗上有问题的疾病)中的有用作用。

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