Padilla- Carmencita D, Cutiongco Eva Maria, Sia Joseph Martin
Institute of Human Genetics, National Institutes of Health, University of the Philippines, Manila.
Southeast Asian J Trop Med Public Health. 2003;34 Suppl 3:239-43.
In the Philippines, congenital anomalies rank among the top 20 causes of death across the life span and are already the third leading cause of death in the infancy period (Philippine Department of Health, 1996). Despite the magnitude of the problem, no formal systematic registration of birth defects has been done in the country up until 1999. Various attempts have been made by different study groups to gather data but there was never a formal effort to consolidate the information and establish a centralized registry. Data from various modes of ascertainment are hereby presented: 1) Philippine Birth Defects Registry Project, 2) Hospital In-Patient and Out-Patient Registries, 3) Prenatal Inventory and Neonatal Outcome Study Group, 4) Hospital Pathology Reports, and 5) Community Outreach Programs. Birth Defects Registry Project had the largest reporting of the different methods presented here. The most common birth defects were multiple congenital anomalies, congenital malformations of the tongue, mouth, and pharynx (ankyloglossia), cleft palate with cleft lip, Down Syndrome, congenital deformities of the feet (talipes equinovarus), anencephaly, other congenital malformations of the face and neck, congenital malformations of the musculoskeletal system (diaphragmatic hernia, gastroschisis), hypospadias, congenital hydrocephalus, polydactyly, syndactyly, and cleft lip.
在菲律宾,先天性异常位列全生命周期前20大死因之中,并且在婴儿期已成为第三大死因(菲律宾卫生部,1996年)。尽管该问题严重,但直到1999年该国都未对出生缺陷进行正式的系统登记。不同研究小组曾多次尝试收集数据,但从未有过正式努力来整合这些信息并建立一个集中登记处。现将通过各种确定方式获得的数据呈现如下:1)菲律宾出生缺陷登记项目;2)医院住院和门诊登记;3)产前清单和新生儿结局研究小组;4)医院病理报告;5)社区外展项目。出生缺陷登记项目在此处列出的不同方法中报告数量最多。最常见的出生缺陷包括多发性先天性异常、舌、口和咽部先天性畸形(舌系带过短)、唇腭裂、唐氏综合征、足部先天性畸形(马蹄内翻足)、无脑儿、面部和颈部其他先天性畸形、肌肉骨骼系统先天性畸形(膈疝、腹裂)、尿道下裂、先天性脑积水、多指(趾)畸形、并指(趾)畸形和唇裂。