Effect of pravastatin on cerebral infarcts and white matter lesions.
作者信息
ten Dam V H, van den Heuvel D M J, van Buchem M A, Westendorp R G J, Bollen E L E M, Ford I, de Craen A J M, Blauw G J
机构信息
Department of Internal Medicine, Leiden University Medical Center, The Netherlands.
出版信息
Neurology. 2005 May 24;64(10):1807-9. doi: 10.1212/01.WNL.0000161844.00797.73.
Abstract
The authors examined the effect of pravastatin 40 mg daily on the progression of ischemic brain lesions using repeated brain MRI. After a mean treatment period of 33 months, there was an increase in total ischemic lesion load of 1.1 cm3 (p < 0.001) in the 270 placebo-treated subjects and 1.1 cm3 (p < 0.001) in the 265 pravastatin-treated subjects. There was no difference between the two treatment groups (p = 0.73).
摘要
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