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经皮球囊压迫术治疗三叉神经痛:基于球囊压迫压力监测的56例患者的结果

Percutaneous balloon compression for the treatment of trigeminal neuralgia: results in 56 patients based on balloon compression pressure monitoring.

作者信息

Brown Jeffrey A, Pilitsis Julie G

机构信息

Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, Michigan, USA.

出版信息

Neurosurg Focus. 2005 May 15;18(5):E10. doi: 10.3171/foc.2005.18.5.11.

Abstract

OBJECT

Percutaneous balloon compression is an effective and technically simple method for treating trigeminal neuralgia (TN). Nevertheless, dysesthesias (10-20%) and masseter muscle weakness (66%) following the procedure have been noted. The purpose of this study was to evaluate the results of testing TN with percutaneous balloon compression aided by intraluminal pressure monitoring.

METHODS

In this study the authors review the results and complications associated with percutaneous balloon compression by using intraluminal pressure monitoring data obtained in 65 procedures performed in 56 consecutive patients over 4 years. The mean patient age was 71 years (range 37-92 years), and the mean follow-up duration was 17 months (range 3-38 months). The mean intraluminal compression pressure was (1160 +/- 62 mm Hg), and the mean duration of compression was 1.15 +/- 0.27 minutes. The trigeminal depressor response was observed in 60 (92%) of 65 procedures, and initial pain relief occurred in 92% of patients. The recurrence rate in patients who had initial relief was 16% (nine of 56). The mean time until recurrence in patients who experienced pain relief after surgery was 13 months (range 3-23 months). Mild numbness immediately after surgery was observed in 83% of patients. At the most recent evaluation, 17% of patients reported persistent, nontroublesome numbness and none had moderate or severe numbness. Minor dysesthesia was present in two patients (4%). Mild masseter muscle weakness occurred in 24% of patients and resolved within a maximum period of 1 year. No patient experienced anesthesia dolorosa, corneal keratitis, or other cranial nerve deficits. These morbidity rates are lower than the incidence reported in the literature when pressure monitoring is not used.

CONCLUSIONS

These data show that by monitoring compression pressure and limiting the duration of compression, it is possible to reduce the incidence of dysesthesias, severe numbness, and masseter weakness after surgery without increasing the rate of recurrent pain in patients with classic TN.

摘要

目的

经皮球囊压迫术是治疗三叉神经痛(TN)的一种有效且技术上简单的方法。然而,术后已发现存在感觉异常(10%-20%)和咬肌无力(66%)。本研究的目的是评估在腔内压力监测辅助下经皮球囊压迫术测试TN的结果。

方法

在本研究中,作者回顾了连续4年对56例患者进行的65例手术中通过腔内压力监测获得的数据,以及与经皮球囊压迫术相关的结果和并发症。患者的平均年龄为71岁(范围37-92岁),平均随访时间为17个月(范围3-38个月)。平均腔内压迫压力为(1160±62mmHg),平均压迫持续时间为1.15±0.27分钟。65例手术中有60例(92%)观察到三叉神经降压反应,92%的患者初始疼痛得到缓解。初始缓解患者的复发率为16%(56例中的9例)。术后疼痛缓解患者复发的平均时间为13个月(范围3-23个月)。83%的患者术后立即出现轻度麻木。在最近一次评估时,17%的患者报告有持续的、不困扰的麻木,无患者有中度或重度麻木。2例患者(4%)出现轻微感觉异常。24%的患者出现轻度咬肌无力,最长在1年内恢复。无患者出现痛性麻木、角膜角膜炎或其他颅神经缺损。这些发病率低于未使用压力监测时文献报道的发生率。

结论

这些数据表明,通过监测压迫压力并限制压迫持续时间,可以降低经典TN患者术后感觉异常、严重麻木和咬肌无力的发生率,而不增加复发疼痛的发生率。

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