Synthesis of novel palladium OCN-pincer complexes: unprecedented sequential C(sp3)-H activation and aerobic oxidation in the reaction of N,N-dialkyl-3-[(N,N-dimethylamino)methyl]-2-iodoanilines with Pd2(dba)3.

作者信息

Solé Daniel, Vallverdú Lluís, Solans Xavier, Font-Bardia Mercé

机构信息

Laboratori de Química Orgànica, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII s/n, 08028-Barcelona, Spain.

出版信息

Chem Commun (Camb). 2005 Jun 7(21):2738-40. doi: 10.1039/b502854j. Epub 2005 Apr 15.

DOI:10.1039/b502854j

PMID:15917938

Abstract

The reaction of N,N-dialkyl-3-[(N,N-dimethylamino)methyl]-2-iodoanilines with Pd2(dba)3 under O2 gives palladium OCN-pincer complexes by means of an unprecedented process that involves the formal aerobic oxidation of C(sp3)-H bonds at the alpha position of the aniline N atom.

摘要