Upadya A, Tilluckdharry L, Nagy C D, Ravichandran P, Manthous C
Bridgeport Hospital, Yale-New Haven Health, 267 Grant Street, Bridgeport, CT 06610-0120, USA.
Eur Respir J. 2005 Jun;25(6):1117-20. doi: 10.1183/09031936.05.00120904.
Herpes simplex virus (HSV) causes tracheobronchitis and pneumonitis; however, to date, there has only been one report of an endobronchial mass caused by HSV type II. This case study describes a 68-yr-old female with severe kyphoscoliosis who was intubated for acute on chronic hypercapnic respiratory failure and developed blood-tinged endotracheal secretions. Fibreoptic bronchoscopy demonstrated an endobronchial mass in the right middle lobe. Cultures grew HSV type I and biopsy specimens demonstrated cytopathological changes consistent with HSV infection. This is the first reported case of HSV type I presenting as an endobronchial tumour.
单纯疱疹病毒(HSV)可引起气管支气管炎和肺炎;然而,迄今为止,仅有一例关于II型HSV引起支气管内肿块的报告。本病例研究描述了一名68岁患有严重脊柱后凸侧弯的女性,因慢性高碳酸血症呼吸衰竭急性发作而插管,并出现带血的气管内分泌物。纤维支气管镜检查显示右中叶有一个支气管内肿块。培养物培养出I型HSV,活检标本显示出与HSV感染一致的细胞病理学变化。这是首例报告的I型HSV表现为支气管内肿瘤的病例。