McCabe Sean Esteban
University of Michigan, Substance Abuse Research Center, 2025 Traverwood Dr., Suite C, Ann Arbor, MI 48105-2194, USA.
Drug Alcohol Depend. 2005 Jul;79(1):53-62. doi: 10.1016/j.drugalcdep.2004.12.006.
This study examined the prevalence and correlates associated with the nonmedical use of prescription benzodiazepine anxiolytics among U.S. college students. This study analyzed data from a nationally representative sample of 10,904 randomly selected students attending 119, 4-year U.S. colleges in 2001. The lifetime prevalence of nonmedical prescription benzodiazepine anxiolytic use was 7.8%, past year prevalence was 4.5% and past month was 1.6%. Past year rates of nonmedical use of prescription anxiolytics ranged from zero percent at the lowest use schools to 20% at the highest use school. Multivariate regression analyses indicated nonmedical use was more likely to occur among college students who were White, had both male and female sex partners and reported higher rates of substance use and other risky behaviors. In addition, nonmedical use of prescription benzodiazepine anxiolytics was less likely to occur among college students who attended college in the North Central region of the U.S. or historically black colleges and universities (HBCUs). This study provides evidence that the nonmedical use of prescription benzodiazepine anxiolytics represents a problem on some college campuses and among certain subgroups of U.S. college students. These findings have important implications for developing prevention efforts aimed at reducing the nonmedical use of prescription benzodiazepine anxiolytics among college students while not hindering the effective clinical treatment for various anxiety disorders.
本研究调查了美国大学生中处方苯二氮䓬类抗焦虑药非医疗用途的流行情况及其相关因素。该研究分析了2001年从美国119所四年制大学随机抽取的10904名具有全国代表性的学生的数据。处方苯二氮䓬类抗焦虑药非医疗用途的终生患病率为7.8%,过去一年的患病率为4.5%,过去一个月的患病率为1.6%。过去一年中,处方抗焦虑药非医疗用途的发生率在使用最少的学校为零,在使用最多的学校为20%。多变量回归分析表明,非医疗用途更有可能发生在白人、有男性和女性性伴侣且报告物质使用和其他危险行为发生率较高的大学生中。此外,在美国中北部地区上大学的学生或历史上的黑人学院和大学(HBCUs)的大学生中,处方苯二氮䓬类抗焦虑药的非医疗用途发生的可能性较小。本研究提供了证据,表明处方苯二氮䓬类抗焦虑药的非医疗用途在一些大学校园和美国大学生的某些亚群体中是一个问题。这些发现对于制定预防措施具有重要意义,这些措施旨在减少大学生中处方苯二氮䓬类抗焦虑药的非医疗用途,同时不妨碍对各种焦虑症的有效临床治疗。