对未来献血者进行血红蛋白筛查：不同血样及不同定量方法的比较

Hemoglobin screening in prospective blood donors: comparison of different blood samples and different quantitative methods.

作者信息

Radtke Hartmut, Polat Gülnur, Kalus Ulrich, Salama Abdulgabar, Kiesewetter Holger

机构信息

Charité-University Medicine Berlin, Institute of Transfusion Medicine, 10098 Berlin, Germany.

出版信息

Transfus Apher Sci. 2005 Aug;33(1):31-5. doi: 10.1016/j.transci.2004.11.004.

DOI:10.1016/j.transci.2004.11.004

PMID:15951241

Abstract

Portable photometers are increasingly used for hemoglobin screening in blood centers. In a total of 500 unselected prospective blood donors, venous hemoglobin concentrations were measured using a hematology analyzer, and fingerstick hemoglobin concentrations were measured on both a HemoCue B and a Biotest hemoglobin photometer. In 100 of the donors, earstick hemoglobin levels were also measured on the HemoCue system. The mean hemoglobin levels in the fingerstick samples were slightly higher than those in the venous samples. The deviation exceeded the limit of +/-10g l(-1) in 9% of samples tested by HemoCue and in 20% of those investigated by Biotest. The use of earstick samples led to considerable overestimation of the actual hemoglobin concentration.

摘要

便携式光度计在血液中心越来越多地用于血红蛋白筛查。在总共500名未经筛选的前瞻性献血者中，使用血液学分析仪测量静脉血红蛋白浓度，并在HemoCue B和Biotest血红蛋白光度计上测量手指血血红蛋白浓度。在100名献血者中，还使用HemoCue系统测量了耳垂血血红蛋白水平。手指血样本中的平均血红蛋白水平略高于静脉血样本。在HemoCue检测的9%的样本和Biotest检测的20%的样本中，偏差超过了±10g l(-1)的限度。使用耳垂血样本导致实际血红蛋白浓度被大幅高估。