来自卢氏薰衣草的坏死单萜类化合物。

Necrodane monoterpenoids from Lavandula luisieri.

作者信息

Baldovini Nicolas, Lavoine-Hanneguelle Sophie, Ferrando Georges, Dusart Ghislaine, Lizzani-Cuvelier Louisette

机构信息

Laboratoire Arômes, Synthèses et Interactions, Faculté des Sciences de Nice-Sophia Antipolis, Parc Valrose, F-06108 Nice Cedex 2, France.

出版信息

Phytochemistry. 2005 Jul;66(14):1651-5. doi: 10.1016/j.phytochem.2005.04.040.

DOI:10.1016/j.phytochem.2005.04.040

PMID:15953623

Abstract

Four new irregular monoterpenoids were identified in the essential oil of Lavandula luisieri (Rozeira) Riv. Mart., a Labiatae endemic to the Iberian Peninsula. By means of spectroscopic and chemical methods, they were characterised as 3,5-dimethylene-1,4,4-trimethylcyclopentene, 5-methylene-2,3,4,4-tetramethylcyclopent-2-enone, 3,4,5,5-tetramethylcyclopenta-1,3-dienecarboxaldehyde and 3,4,5,5-tetramethylcyclopenta-1,3-dienecarboxylic acid. L. luisieri essential oil and extract showed a good activity against Candida albicans and gram positive bacteria: Staphylococcus aureus, S. epidermidis and S. pyogenes.

摘要

在伊比利亚半岛特有的唇形科植物卢氏薰衣草（Lavandula luisieri (Rozeira) Riv. Mart.）的精油中鉴定出四种新的不规则单萜类化合物。通过光谱和化学方法，它们被鉴定为3,5-二亚甲基-1,4,4-三甲基环戊烯、5-亚甲基-2,3,4,4-四甲基环戊-2-烯酮、3,4,5,5-四甲基环戊-1,3-二烯甲醛和3,4,5,5-四甲基环戊-1,3-二烯羧酸。卢氏薰衣草精油和提取物对白色念珠菌和革兰氏阳性菌：金黄色葡萄球菌、表皮葡萄球菌和化脓性链球菌表现出良好的活性。