Bhattathiri P S, Ramakrishnan Y, Vivar R A, Bell K, Bullock R E, Mitchell P, Gregson B, Mendelow A D
Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, UK.
Acta Neurochir (Wien). 2005 Aug;147(8):839-45. doi: 10.1007/s00701-005-0548-9. Epub 2005 Jun 16.
Carotid Endarterectomy can be performed under local, regional or general anaesthesia. One of the most important effects of the type of anaesthetic used is on the systemic blood pressure. Although variations in blood pressure during and following carotid endarterectomy have been studied previously, the effects of awake carotid endarterectomy under local anaesthesia on blood pressure and its comparison with similar procedures under similar types of anaesthesia have not.
Peri-operative blood pressure measurements were collected from the records of 25 consecutive patients for each of the following five procedures; Carotid Endarterectomy under general anaesthesia (CEAGA), Anterior Cervical Discectomy and Fusion under general anaesthesia (ACDF), Cerebral Angiography under local anaesthesia (ANG), Carotid Endarterectomy patients under local anaesthesia who were symptomatic (CEALAS) and Carotid Endarterectomy patients under local anaesthesia who were asymptomatic (CEALAA). The recordings were then analysed to find out if there were any clinically significant variations in peri-operative blood pressure.
There is a significant and consistent difference when the pre-operative value was compared with the 4 hour and 24 hour post-operative recordings between the local and general anaesthetic groups for carotid endarterectomy. Carotid endarterectomy reduces the systolic and diastolic blood pressures post-operatively when performed under local anaesthesia and only the diastolic pressure was reduced when performed under general anaesthesia.
The study provides evidence about the effect of carotid endarterectomy on the systemic blood pressure and its variations when performed under different types of anaesthesia. There is significant post-operative reduction in both the systolic and diastolic blood pressure values and the intraoperative fluctuation is minimal when local anaesthesia is used. Further studies are required to find out how this affects the long-term blood pressure and clinical outcome of the patient.
颈动脉内膜切除术可在局部、区域或全身麻醉下进行。所用麻醉类型最重要的影响之一是对全身血压的影响。尽管先前已经研究了颈动脉内膜切除术期间及之后的血压变化,但局部麻醉下清醒状态的颈动脉内膜切除术对血压的影响及其与类似麻醉类型下类似手术的比较尚未得到研究。
从以下五种手术的连续25例患者的记录中收集围手术期血压测量值;全身麻醉下的颈动脉内膜切除术(CEAGA)、全身麻醉下的颈椎前路椎间盘切除术和融合术(ACDF)、局部麻醉下的脑血管造影术(ANG)、有症状的局部麻醉下的颈动脉内膜切除术患者(CEALAS)和无症状的局部麻醉下的颈动脉内膜切除术患者(CEALAA)。然后对记录进行分析,以确定围手术期血压是否存在任何具有临床意义的变化。
在颈动脉内膜切除术的局部麻醉组和全身麻醉组中,术前值与术后4小时和24小时记录值相比存在显著且一致的差异。局部麻醉下进行颈动脉内膜切除术时,术后收缩压和舒张压均降低,而全身麻醉下进行时仅舒张压降低。
该研究提供了关于颈动脉内膜切除术对全身血压的影响及其在不同类型麻醉下的变化的证据。使用局部麻醉时,术后收缩压和舒张压值均显著降低,术中波动最小。需要进一步研究以确定这如何影响患者的长期血压和临床结局。