Verachai Viroj, Phutiprawan Tipwan, Sawanpanyalert Pathom
Department of Medical Services, Thanyarak Institute on Drug Abuse, Pathumthani 12130, Thailand.
J Med Assoc Thai. 2005 Jan;88(1):76-9.
A study of HIV infection among substance abusers from 1987 to 2002 was performed in Thanyarak Institute on Drug Abuse (TIDA). From 118,676 anti HIV tests (6,076 - 10,626 tests each year) of TIDA inpatients, 17,526 tests were positive (474 - 2,041 tests each year) In 71,403 new substance abuse cases (3,724 - 6,184 cases each year), 12,401 cases were positive (17.4%), highest in 1990 28.3% and then decreased to 8% in the last three years. In injecting drug users (IDU), the mean anti HIV positivity rate was 21.7% (range 19.2 - 29.4%) higher than those among non IDU about 8 times 2.8% (range 1.9 - 3.6%). The HIV incidence rates were from inpatients that were previously anti-HIV negative, the authors found the mean incidence rate was 7.3% per year. Anti HIV positive cases were highest in injecting heroin users (IHU) about 36.8% (range 31.5 - 46.1%). Although numbers of IHU in Thailand have decreased in the last 6 years because of changing to use methamphetamine by smoking and dying from HIV subtype B'. The authors must continue the effective preventive programs of both avoid sharing injecting equipments and promoting 100% condom program to control this reservoir of HIV infection.
1987年至2002年期间,在Thanarak药物滥用研究所(TIDA)对药物滥用者中的艾滋病毒感染情况进行了一项研究。在TIDA住院患者的118,676次抗艾滋病毒检测(每年6,076 - 10,626次检测)中,有17,526次检测呈阳性(每年474 - 2,041次检测)。在71,403例新的药物滥用病例(每年3,724 - 6,184例)中,有12,401例呈阳性(17.4%),1990年最高,为28.3%,随后在过去三年中降至8%。在注射吸毒者(IDU)中,抗艾滋病毒阳性率平均为21.7%(范围为19.2 - 29.4%),比非IDU中的阳性率约高8倍,为2.8%(范围为1.9 - 3.6%)。作者发现,以前抗艾滋病毒阴性的住院患者的艾滋病毒发病率平均为每年7.3%。抗艾滋病毒阳性病例在注射海洛因使用者(IHU)中最高,约为36.8%(范围为31.5 - 46.1%)。尽管泰国的IHU数量在过去6年中有所减少,原因是转向通过吸烟使用甲基苯丙胺以及死于B型艾滋病毒亚型。作者必须继续实施有效的预防计划,包括避免共用注射设备和推广100%使用避孕套计划,以控制这一艾滋病毒感染源。