Rose John S, Richards John R, Battistella Felix, Bair Aaron E, McGahan John P, Kuppermann Nathan
Department of Emergency Medicine, University of California, Davis School of Medicine, Sacramento, California 95817, USA.
J Emerg Med. 2005 Jul;29(1):15-21. doi: 10.1016/j.jemermed.2005.01.004.
The object of this study was to derive a clinical decision rule for therapeutic laparotomy among adult blunt trauma patients with a positive abdominal ultrasound for trauma (FAST) examination.
We retrospectively reviewed the trauma registry and medical records of all critical trauma patients who underwent a FAST examination in the emergency department (ED) in a university Level I trauma center over a 3-year period. Blunt trauma patients aged >16 years who had a positive FAST examination (defined as the presence of intraperitoneal fluid) were eligible. We selected seven clinical and ultrasound variables available during ED resuscitation for analysis: age, presence of an episode of hypotension (systolic blood pressure <90 torr in the ED), presence of abdominal tenderness, chest injury, pelvic fracture, femur fracture, and FAST fluid location (right upper quadrant [RUQ] only; RUQ plus other location; other location only). The primary outcome variable was whether a laparotomy was performed and whether this laparotomy was needed to provide the definitive surgical intervention ("therapeutic laparotomy"). We analyzed the variables using binary recursive partitioning analysis to create a decision rule.
There were 2336 FAST examinations performed during the study period, resulting in 230 (9.8%) positive examinations in patients meeting inclusion criteria. There were 135 patients who had therapeutic laparotomies and 95 who did not need laparotomy. The groups were similar in baseline characteristics. In the recursive partitioning analysis, the first node in the decision tree was the presence of fluid in the RUQ. Of the 144 patients with RUQ fluid, 105 (73%, 95% confidence interval [CI] 64%-80%) required therapeutic laparotomy. Of the 86 patients without RUQ fluid, 30 (35%, 95% CI 25%-46%) nevertheless required therapeutic laparotomies, and the variables blood pressure, femur fracture, abdominal tenderness, and age further divided these patient into high- and low-risk groups. Of the 12 patients without RUQ fluid who had normal blood pressures, no femur fractures, no abdominal tenderness, and were aged 60 years and younger, none (95% CI 0%-22%) required therapeutic laparotomy. In conclusion, given a positive FAST examination, the presence of fluid in the RUQ is an important predictor of the need for therapeutic laparotomy.
In the absence of fluid in the RUQ, there are other clinical variables that may allow for the development of a clinical decision rule regarding the need for therapeutic laparotomy.
本研究的目的是为腹部创伤超声检查(FAST)呈阳性的成年钝性创伤患者推导一项治疗性剖腹手术的临床决策规则。
我们回顾性分析了一所大学一级创伤中心在3年期间急诊科所有接受FAST检查的重症创伤患者的创伤登记资料和病历。纳入标准为年龄大于16岁且FAST检查呈阳性(定义为存在腹腔内积液)的钝性创伤患者。我们选择了急诊复苏期间可用的7个临床和超声变量进行分析:年龄、是否有低血压发作(急诊科收缩压<90托)、是否有腹部压痛、胸部损伤、骨盆骨折、股骨骨折以及FAST检查发现的积液位置(仅右上腹[RUQ];右上腹加其他位置;仅其他位置)。主要结局变量是是否进行了剖腹手术以及该剖腹手术是否为提供确定性手术干预所必需(“治疗性剖腹手术”)。我们使用二元递归划分分析对变量进行分析以制定决策规则。
研究期间共进行了2336次FAST检查,符合纳入标准的患者中有230次(9.8%)检查呈阳性。有135例患者接受了治疗性剖腹手术,95例患者不需要剖腹手术。两组患者的基线特征相似。在递归划分分析中,决策树的第一个节点是右上腹是否存在积液。在144例右上腹有积液的患者中,105例(73%,95%置信区间[CI] 64%-80%)需要进行治疗性剖腹手术。在86例右上腹无积液的患者中,仍有30例(35%,95%CI 25%-46%)需要进行治疗性剖腹手术,血压、股骨骨折、腹部压痛和年龄等变量进一步将这些患者分为高风险组和低风险组。在12例右上腹无积液、血压正常、无股骨骨折、无腹部压痛且年龄在60岁及以下的患者中,无人(95%CI 0%-22%)需要进行治疗性剖腹手术。总之,在FAST检查呈阳性的情况下,右上腹存在积液是需要进行治疗性剖腹手术的重要预测指标。
在右上腹无积液的情况下,还有其他临床变量可用于制定关于是否需要进行治疗性剖腹手术的临床决策规则。