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暴力行为、不当行为与精神分裂症:四年最佳治疗后的结果

Violence, misconduct and schizophrenia: Outcome after four years of optimal treatment.

作者信息

Economou Marina, Palli Alexandra, Falloon Ian Rh

机构信息

Department of Psychiatry, University of Auckland, New Zealand.

出版信息

Clin Pract Epidemiol Ment Health. 2005 Apr 28;1(1):3. doi: 10.1186/1745-0179-1-3.

Abstract

BACKGROUND

Aggressive behaviour in patients with schizophrenic disorders is an ongoing source of concern to community-based services. It has been suggested that optimal treatment may reduce the risk of serious misconduct. OBJECTIVE: To assess prospectively aggressive and sexual misconduct in a cohort of patients receiving continued evidence-based community treatment. METHOD: Fifty patients with a DSM-IV diagnosis of a schizophrenic disorder were treated for 4 years with integrated biomedical and psychosocial strategies. The frequency and context of all aggressive and sexually inappropriate behaviour were assessed throughout. Correlations between an index of misconduct and demographic and clinical variables were examined. RESULTS: Levels of serious misconduct were low at the start of the project and declined as treatment progressed. Close examination of predictors of misconduct supported larger epidemiological studies imputing persistent psychotic symptoms, personality disorders and substance use. CONCLUSION: The study supports the hypothesis that effective treatment reduces aggressive and sexual misconduct in schizophrenic disorders.

摘要

背景

精神分裂症患者的攻击性行为一直是社区服务持续关注的问题。有人认为,最佳治疗可能会降低严重不当行为的风险。目的:前瞻性评估一组接受持续循证社区治疗的患者的攻击性行为和性不当行为。方法:50名符合《精神疾病诊断与统计手册》第四版(DSM-IV)精神分裂症诊断标准的患者接受了为期4年的生物医学与心理社会综合治疗策略。对所有攻击性行为和性不当行为的频率及背景进行全程评估。研究不当行为指数与人口统计学和临床变量之间的相关性。结果:项目开始时严重不当行为的发生率较低,且随着治疗的推进而下降。对不当行为预测因素的仔细研究支持了更大规模的流行病学研究,这些研究将持续的精神病症状、人格障碍和物质使用视为相关因素。结论:该研究支持有效治疗可减少精神分裂症患者攻击性行为和性不当行为这一假设。

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