Elman Igor, Ariely Dan, Mazar Nina, Aharon Itzhak, Lasko Natasha B, Macklin Michael L, Orr Scott P, Lukas Scott E, Pitman Roger K
Department of Psychiatry, McLean Hospital and Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA.
Psychiatry Res. 2005 Jun 30;135(3):179-83. doi: 10.1016/j.psychres.2005.04.002.
Reward dysfunction may be implicated in post-traumatic stress disorder (PTSD). This study applied a behavioral probe, known to activate brain reward regions, to subjects with PTSD. Male heterosexual Vietnam veterans with (n = 12) or without (n = 11) current PTSD were administered two tasks: (a) key pressing to change the viewing time of average or beautiful female or male facial images, and (b) rating the attractiveness of these images. There were no significant group differences in the attractiveness ratings. However, PTSD patients expended less effort to extend the viewing time of the beautiful female faces. These findings suggest a reward deficit in PTSD.
奖赏功能障碍可能与创伤后应激障碍（PTSD）有关。本研究对患有PTSD的受试者应用了一种已知能激活大脑奖赏区域的行为探测法。患有（n = 12）或未患有（n = 11）当前PTSD的男性异性恋越南退伍军人接受了两项任务：（a）按键以改变平均或美丽女性或男性面部图像的观看时间，以及（b）对这些图像的吸引力进行评分。吸引力评分方面没有显著的组间差异。然而，PTSD患者花费较少的努力来延长美丽女性面孔的观看时间。这些发现表明PTSD存在奖赏缺陷。
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