与肺球孢子菌病相关的Sweet综合征（急性发热性嗜中性皮病）
Sweet syndrome (acute febrile neutrophilic dermatosis) associated with pulmonary coccidioidomycosis.
作者信息
DiCaudo David J, Ortiz Karel Jill, Mengden Stephanie J, Lim Katherine K
机构信息
Department of Dermatology, Mayo Clinic, Scottsdale, AZ 85259, USA.
出版信息
Arch Dermatol. 2005 Jul;141(7):881-4. doi: 10.1001/archderm.141.7.881.
BACKGROUND
Sweet syndrome (acute febrile neutrophilic dermatosis) may arise in association with a variety of underlying systemic diseases. Only 1 case of coccidioidomycosis-associated Sweet syndrome has previously been reported.
OBSERVATIONS
We describe 2 patients who developed Sweet syndrome during the onset of acute pulmonary coccidioidomycosis. Systemic antifungal therapy was given in both cases. Respiratory symptoms and skin lesions resolved within 5 weeks.
CONCLUSIONS
Sweet syndrome may be a presenting feature of coccidioidomycosis. Recognition of the underlying pulmonary infection is important so that inappropriate treatment with systemic corticosteroids can be avoided.
背景
Sweet综合征（急性发热性嗜中性皮病）可能与多种潜在的全身性疾病相关。此前仅报告过1例与球孢子菌病相关的Sweet综合征。
观察结果
我们描述了2例在急性肺球孢子菌病发病期间出现Sweet综合征的患者。两例均给予了全身抗真菌治疗。呼吸症状和皮肤病变在5周内消退。
结论
Sweet综合征可能是球孢子菌病的一个表现特征。认识到潜在的肺部感染很重要，这样可以避免不恰当地使用全身性皮质类固醇进行治疗。
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