von Ungern-Sternberg B S, Regli A, Reber A, Schneider M C
Department of Anaesthesia, University Hospital, Basel, Switzerland.
Acta Anaesthesiol Scand. 2005 Aug;49(7):940-8. doi: 10.1111/j.1399-6576.2005.00754.x.
There is limited data comparing the impact of spinal anaesthesia (SA) and general anaesthesia (GA) on perioperative lung function. Here we assessed the differences of these two anaesthetic techniques on perioperative lung volumes in normal-weight (BMI < 25) and overweight (BMI 25-30) patients using spirometry.
We prospectively studied 84 consenting patients having operations in the vaginal region receiving either GA (n = 41) or SA (n = 43). Both groups (GA and SA) were further divided into two subgroups each (normal-weight vs. overweight). We measured vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), midexpiratory (MEF25-75) and peak expiratory flow rates (PEFR) at the preoperative assessment (baseline), after premedication, after effective SA, and 20 min, 1 h, 2 h and 3 h after the operation (last measurement after patient mobilization).
Premedication was associated with a small but significant decrease in lung volumes in direct correlation with BMI (-5%). Spinal anaesthesia resulted in a significant reduction in lung volumes in overweight as opposed to normal-weight patients. Postoperatively, lung volumes were significantly more reduced following GA than SA as indicated by differences in mean VC (SD) of -12 (6)% vs. -6 (5)% 20 min after the end of the operation in the normal-weight and -18 (5)% vs. -10 (5)% in the overweight patients. There was a significant impact of BMI on postoperative respiratory function, which was significantly more important in the GA group than in the SA group, and recovery of lung volumes was more rapid in the normal-weight patients than in the overweight patients, particularly in the SA group.
In gynaecological patients undergoing vaginal surgery, the impact of anaesthesia on postoperative lung function as assessed by spirometry was significantly less after SA than GA, particularly in overweight patients.
比较脊髓麻醉(SA)和全身麻醉(GA)对围手术期肺功能影响的数据有限。在此,我们使用肺活量测定法评估了这两种麻醉技术对正常体重(BMI<25)和超重(BMI 25 - 30)患者围手术期肺容量的差异。
我们前瞻性地研究了84例同意接受阴道区域手术的患者,其中41例接受GA,43例接受SA。两组(GA和SA)又各自进一步分为两个亚组(正常体重与超重)。我们在术前评估(基线)、术前用药后、有效SA后以及术后20分钟、1小时、2小时和3小时(患者活动后的最后一次测量)测量肺活量(VC)、用力肺活量(FVC)、第1秒用力呼气量(FEV1)、呼气中期流量(MEF25 - 75)和呼气峰值流速(PEFR)。
术前用药与肺容量的小幅但显著降低相关,且与BMI直接相关(-5%)。与正常体重患者相比,脊髓麻醉导致超重患者的肺容量显著降低。术后,如正常体重患者术后20分钟平均VC(标准差)差异为-12(6)% 与 -6(5)%,超重患者为-18(5)% 与 -10(5)%所示,GA后肺容量的降低明显大于SA。BMI对术后呼吸功能有显著影响,在GA组比SA组更显著,且正常体重患者的肺容量恢复比超重患者更快,尤其是在SA组。
在接受阴道手术的妇科患者中,通过肺活量测定法评估,SA后麻醉对术后肺功能的影响明显小于GA,尤其是在超重患者中。