Acute monocytic leukemia with (8;22)(p11;q13) translocation. Involvement of 8p11 as in classical t(8;16)(p11;p13).
作者信息
Lai J L, Zandecki M, Fenaux P, Preudhomme C, Facon T, Deminatti M
机构信息
Service de Cytogénétique, Faculté de Médecine Lille, France.
出版信息
Cancer Genet Cytogenet. 1992 Jun;60(2):180-2. doi: 10.1016/0165-4608(92)90013-x.
PMID:1606561
Abstract
A new case of acute monocytic leukemia observed in a 73-year-old male (ANLLM5) with an unusual t(8;22)(p11;q13) is reported. The blasts did not demonstrate erythrophagocytosis, but the presence of both naphthol-ASD-chloro-acetate esterase and butyrate esterase activities was similar to that seen in cases with t(8;16)(p11;p13). Involvement of the 8p11 region in ANLLM4 and M5 is discussed, being the third most frequent rearrangement in acute leukemia with monocytic components seen at our Center.
摘要
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