Zhang Rong, Yu Yan, Du Jun-rong, Liu Jian, Zhang Jie, Wei Ting, Li Xin, Li Jiang, Long Rui
West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Zhongguo Zhong Yao Za Zhi. 2005 May;30(10):785-8.
To study the influence of Xinqin tablets on guinea-pig nasal hypersensitivity.
2,4-Toluene Diisocyanate (TDI) was selected as antigen and used in nose to establish guinea-pig allergic rhinitis. The effects of Xinqin tablets on symptoms of nasal hypersensitivity in guinea-pigs, histamine content of nasal mucosa and activity of nitric oxide synthase (NOS) were examined.
Xinqin tablets could significantly relieve the pathological symptoms of nasal hypersensitivity in guinea-pig, reduce histamine content of nasal mucosa and inhibit the activity of nitric oxide synthase.
Xinqin tablets have significant effect on nasal hypersensitivity, and prevent the occurrence of allergic rhinitis.
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