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头颈癌治疗后慢性吞咽困难的严重程度和持续时间。

Severity and duration of chronic dysphagia following treatment for head and neck cancer.

作者信息

Nguyen Nam P, Moltz Candace C, Frank Cheryl, Karlsson Ulf, Smith Herbert J, Nguyen Phuc D, Vos Paul, Nguyen Ly M, Rose Sue, Dutta Suresh, Sallah Sabah

机构信息

Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75216, USA.

出版信息

Anticancer Res. 2005 Jul-Aug;25(4):2929-34.

Abstract

UNLABELLED

The purpose of this investigation was to evaluate chronic dysphagia (lasting 3 or more months) following treatment for head and neck cancer. Since dysphagia is a common sequela post therapy in cancer survivors, it may be helpful for the clinician to be aware of the persistence of dysphagia as well as its usual severity. Modified Barium Swallow (MBS) examinations were performed in cancer-free patients who complained of dysphagia following treatment for head and neck cancer. The severity of the dysphagia was graded on a scale of 1 to 7. Each patient had sequential MBS and underwent swallowing therapy in between. The severity of dysphagia was compared between the first and last MBS study to determine whether the swallowing function had returned to normal.

RESULTS

Between 1996 and 2004, 12 patients with dysphagia underwent repeated MBS following treatment. Swallowing function did not return to normal in all patients. At a median time of 29 months following treatment (range 8 to 94 months), the severity of dysphagia decreased in 8 patients (67%), remained unchanged in 3 patients (25%) and worsened in 1 patient (8%). Chronic dysphagia following treatment is unlikely to resolve with time despite rehabilitation therapy. Excessive scarring following treatment may be responsible for the persistence and severity of dysphagia. Physicians should be aware of the long-term effects of dysphagia on patient nutrition and psychological well-being.

摘要

未标记

本研究的目的是评估头颈癌治疗后的慢性吞咽困难(持续3个月或更长时间)。由于吞咽困难是癌症幸存者治疗后的常见后遗症,临床医生了解吞咽困难的持续情况及其通常的严重程度可能会有所帮助。对治疗后头颈癌后出现吞咽困难的无癌患者进行了改良钡餐吞咽(MBS)检查。吞咽困难的严重程度按1至7级进行分级。每位患者都进行了连续的MBS检查,并在其间接受吞咽治疗。比较首次和末次MBS研究中吞咽困难的严重程度,以确定吞咽功能是否已恢复正常。

结果

1996年至2004年期间,12例吞咽困难患者在治疗后接受了重复的MBS检查。并非所有患者的吞咽功能都恢复正常。在治疗后的中位时间29个月(范围8至94个月)时,8例患者(67%)的吞咽困难严重程度降低,3例患者(25%)保持不变,1例患者(8%)病情恶化。尽管进行了康复治疗,治疗后的慢性吞咽困难不太可能随时间而缓解。治疗后过多的瘢痕形成可能是吞咽困难持续存在和严重的原因。医生应意识到吞咽困难对患者营养和心理健康的长期影响。

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