Cohen Laurie E
Division of Endocrinology, Children's Hospital Boston, Boston, MA 02115, USA.
Endocrinol Metab Clin North Am. 2005 Sep;34(3):769-89, xi. doi: 10.1016/j.ecl.2005.04.008.
Endocrinopathies are significant consequences of the treatment of childhood cancers. The risk of developing these adverse events is related to the underlying disease and its treatment with cytotoxic agents and radiation therapy. This article reviews hypothalamic-pituitary, thyroid, and gonadal dysfunction, as well as osteopenia-osteoporosis and obesity.
内分泌疾病是儿童癌症治疗的重要后果。发生这些不良事件的风险与基础疾病及其细胞毒性药物和放射治疗有关。本文综述下丘脑 - 垂体、甲状腺和性腺功能障碍,以及骨质减少 - 骨质疏松和肥胖。