Wong N Y, Eu K W
Department of Colorectal Surgery, Singapore General Hospital, Singapore.
Dis Colon Rectum. 2005 Nov;48(11):2076-9. doi: 10.1007/s10350-005-0146-1.
Defunctioning ileostomy or colostomy is still routinely performed after low anterior resection in the belief that diverting the fecal stream will prevent anastomotic dehiscence. However, an ileostomy is not without morbidity for the patient. This study aims to determine if a diverting stoma is really necessary after a low anastomosis.
All low or ultralow anterior resections done in this department were performed by consultant-grade surgeons in a standardized manner. The patients were all monitored closely after surgery for clinical signs of an anastomotic leak. There were 1078 patients who underwent elective low or ultralow anterior resections in a ten-year period between 1994 and 2004. Twelve of them were irradiated before surgery; they were excluded from the study. During a seven-month period from February 2004 through August 2004, 324 patients who underwent such procedures were not defunctioned. These were compared with 742 patients who were previously defunctioned with a proximal stoma. The results were analyzed using the Pearson chi-squared test.
Thirteen (4 percent) patients who were not defunctioned developed a clinical anastomotic leak, whereas the leak rate for those who were defunctioned was 3.8 percent. There was no statistical difference demonstrated. Ninety-five percent of patients who developed a leak required surgical intervention; the remaining 5 percent could be dealt with by radiologic drainage. The overall mortality rate for anastomotic leak in this department is 7.3 percent.
A diverting stoma does not reduce postoperative anastomotic leak rate. Rather, it reduces the otherwise catastrophic effects of an anastomotic leak such as fecal peritonitis and septicemia. An ileostomy carries certain morbidity and also adds to the cost of the entire operation. Therefore, it should not be performed routinely. Instead, it should be performed selectively in patients with poorly prepared bowels, coupled with a distal limb washout, and in patients with significant comorbidities who can ill afford the complications of a leak.
低位前切除术后仍常规施行回肠造口术或结肠造口术,其依据是改道粪便流可预防吻合口裂开。然而,回肠造口术对患者而言并非没有并发症。本研究旨在确定低位吻合术后是否真的需要转流性造口。
本科室所有低位或超低位前切除术均由顾问级外科医生以标准化方式进行。术后对所有患者进行密切监测,观察吻合口漏的临床体征。在1994年至2004年的十年间,有1078例患者接受了择期低位或超低位前切除术。其中12例在术前接受过放疗,被排除在研究之外。在2004年2月至8月的七个月期间,324例接受此类手术的患者未进行造口转流。将这些患者与742例先前进行过近端造口转流的患者进行比较。结果采用Pearson卡方检验进行分析。
未进行造口转流的13例(4%)患者发生了临床吻合口漏,而进行了造口转流的患者漏出率为3.8%。未显示出统计学差异。发生漏出的患者中有95%需要手术干预;其余5%可通过放射引流处理。本科室吻合口漏的总体死亡率为7.3%。
转流性造口并不能降低术后吻合口漏率。相反,它降低了吻合口漏如粪性腹膜炎和败血症等原本灾难性的后果。回肠造口术有一定的并发症,且增加了整个手术的费用。因此,不应常规施行。相反,应在肠道准备不佳的患者中选择性施行,并结合远端肠管冲洗,以及在无法承受吻合口漏并发症的有严重合并症的患者中施行。