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[锁骨远端创伤后骨质溶解。2例病例的解剖病理学研究]

[Post-traumatic osteolysis of the distal extremity of the clavicle. Anatomopathological study of 2 cases].

作者信息

Jeandel P, Garbe L, Dischino M, Martet G, Chouc P Y, Dufour M

机构信息

Service de Rheumatologie, H.I.A. Laveran Marseille.

出版信息

Rev Rhum Mal Osteoartic. 1992 Mar;59(3):207-12.

PMID:1609239
Abstract

Two patients with post-traumatic osteolysis of the distal end of the clavicle undergoing surgery 5 months and 22 months respectively after the initial trauma were evaluated histopathologically. The lysed zone was replaced by tissue of fibrous appearance, with little blood supply and non-inflammatory, the presence of which could be suspected by magnetic resonance. The synovial membrane, non-inflammatory but hypervascularised, participated in the process but did not appear to be directly responsible for the osteolysis. The osseous tissue of the patient, operated upon early, showed signs of osteoclastic resorption but there was neither stasis, vasodilatation nor signs of osteogenesis. These various findings suggest that post-traumatic osteolysis of the distal end of the clavicle does not result from local ischemic events. These appearances seem identical to those described in multifocal primary osteolysis, the cause of which also remains unknown.

摘要

对两名锁骨远端创伤后骨质溶解患者进行了组织病理学评估,这两名患者分别在初次创伤后5个月和22个月接受了手术。溶解区域被纤维样组织取代,血供少且无炎症,磁共振成像可怀疑其存在。滑膜无炎症但血管增生,参与了这一过程,但似乎并非骨质溶解的直接原因。早期接受手术的患者的骨组织显示出破骨细胞吸收的迹象,但既没有血流淤滞、血管扩张,也没有成骨迹象。这些不同的发现表明,锁骨远端创伤后骨质溶解并非由局部缺血事件引起。这些表现似乎与多灶性原发性骨质溶解中描述的表现相同,其病因也仍然未知。

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