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青少年酒精使用障碍可预测成人边缘型人格障碍。

Adolescent alcohol use disorders predict adult borderline personality.

作者信息

Thatcher Dawn L, Cornelius Jack R, Clark Duncan B

机构信息

Pittsburgh Adolescent Alcohol Research Center (PAARC), Department of Psychiatry, University of Pittsburgh Medical Center, USA.

出版信息

Addict Behav. 2005 Oct;30(9):1709-24. doi: 10.1016/j.addbeh.2005.07.008. Epub 2005 Aug 10.

Abstract

BACKGROUND

This study investigated adolescent alcohol use disorders (AUDs) and other characteristics as predictors of adult borderline personality disorder (BPD) symptoms.

METHODS

Adolescents with AUDs (n = 355) were recruited from clinical treatment sources and adolescents without AUDs (n = 169) were recruited from the community. During an adolescent assessment (age 16+/-1.3), childhood physical and/or sexual abuse history, AUDs and associated psychiatric disorders were measured via semi-structured interviews. Symptoms of BPD were measured in a young adult follow-up assessment (age 22+/-2.4). Latent class analysis was utilized to classify individuals into four categories based upon BPD symptom profiles.

RESULTS

Multinomial regression models indicated that adolescent AUDs and other psychiatric disorders mediated the relationship between child physical and/or sexual abuse and adult BPD latent class.

CONCLUSIONS

Results were consistent with a developmental conceptualization of BPD, with AUDs and other adolescent psychopathology antecedents representing developmentally relevant forms of dysregulation, and in their more severe forms culminating in borderline symptomatology.

摘要

背景

本研究调查了青少年酒精使用障碍(AUDs)及其他特征作为成人边缘型人格障碍(BPD)症状预测因素的情况。

方法

从临床治疗机构招募患有酒精使用障碍的青少年(n = 355),从社区招募无酒精使用障碍的青少年(n = 169)。在青少年评估(年龄16±1.3岁)期间,通过半结构化访谈测量童年期身体和/或性虐待史、酒精使用障碍及相关精神障碍。在青年成人随访评估(年龄22±2.4岁)中测量边缘型人格障碍症状。采用潜在类别分析根据边缘型人格障碍症状概况将个体分为四类。

结果

多项回归模型表明,青少年酒精使用障碍及其他精神障碍介导了儿童期身体和/或性虐待与成人边缘型人格障碍潜在类别的关系。

结论

结果与边缘型人格障碍的发展概念一致,酒精使用障碍及其他青少年精神病理学先兆代表了与发展相关的失调形式,其更严重的形式最终导致边缘型症状。

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