肾上腺嗜铬细胞瘤伴显著的周期性血流动力学波动。

Adrenal pheochromocytoma associated with dramatic cyclic hemodynamic fluctuations.

作者信息

Guzik Przemyslaw, Wykretowicz Andrzej, Wesseling Ir Karel H, Wysocki Henryk

出版信息

Int J Cardiol. 2005 Sep 1;103(3):351-3. doi: 10.1016/j.ijcard.2004.08.071.

DOI:10.1016/j.ijcard.2004.08.071

Abstract

A 52-year-old woman with a right adrenal pheochromocytoma had repetitive attacks of symptomatic hypotension/shock with systolic blood pressure (SBP)<50 mmHg followed by hypertension/hypertensive crises with SBP>300 mmHg. A non-invasive recording of beat-to-beat SBP, diastolic blood pressure (DBP), heart rate (HR), stroke volume (SV), cardiac output (CO) and total peripheral resistance (TPR) was collected for 346 min. Twenty hemodynamic cycles occurred during this time, lasting 17 min on average, with the most dramatic changes of TPR. The ratio of the highest to the lowest observed values was nearly 12:1 for TPR, over 6:1 for both SBP and DBP, over 4:1 for CO, and nearly 4:1 for SV and 2:1 for HR. The fluctuations of TPR preceded changes of all other hemodynamic variables.

摘要

一名患有右肾上腺嗜铬细胞瘤的52岁女性出现反复的症状性低血压/休克发作，收缩压（SBP）<50 mmHg，随后出现高血压/高血压危象，SBP>300 mmHg。连续346分钟无创记录逐搏收缩压、舒张压（DBP）、心率（HR）、每搏输出量（SV）、心输出量（CO）和总外周阻力（TPR）。在此期间发生了20个血流动力学周期，平均持续17分钟，TPR变化最为显著。观察到的TPR最高值与最低值之比接近12:1，SBP和DBP均超过6:1，CO超过4:1，SV接近4:1，HR为2:1。TPR的波动先于所有其他血流动力学变量的变化。