Irie Yasuhiko, O'toole George A, Yuk Ming H
Department of Microbiology, University of Pennsylvania School of Medicine, 201C Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104-6084, USA.
FEMS Microbiol Lett. 2005 Sep 15;250(2):237-43. doi: 10.1016/j.femsle.2005.07.012.
We have previously reported that the respiratory pathogen Bordetella bronchiseptica can form biofilms in vitro. In this report, we demonstrate the disruption of B. bronchiseptica biofilms by rhamnolipids secreted from Pseudomonas aeruginosa. This suggests that biosurfactants such as rhamnolipids may be utilized as antimicrobial agents for removing Bordetella biofilms.
我们之前曾报道过呼吸道病原体支气管败血博德特氏菌能够在体外形成生物膜。在本报告中,我们证明了铜绿假单胞菌分泌的鼠李糖脂可破坏支气管败血博德特氏菌的生物膜。这表明诸如鼠李糖脂之类的生物表面活性剂可用作去除博德特氏菌生物膜的抗菌剂。